A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution by Jennifer A. Doudna

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Read A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution Online Free - A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans.
Writing with fellow researcher Samuel Sternberg, Doudna shares the thrilling story of her discovery, and passionately argues that enormous responsibility comes with the ability to rewrite the code of life. With CRISPR, she shows, we have effectively taken control of evolution. What will we do with this unfathomable power?

Title : A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution
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ISBN : 0544716949
Edition Language : English
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Number of Pages : 0 pages


Clif rated it ★★★★☆

July 03, 2017

This book's coauthor, Jennifer Doudna, together with Emmanuelle Charpentier published a seminal 2012 paper that demonstrated that CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) could be used for programmable gene editing. The whole field of CRISPR has since become the hottest...

Rachel (Kalanadi) rated it ★★★★★

August 20, 2017

A great explanation of CRISPR Cas9 that recounts the research that uncovered it and makes a case for determining how we will responsibly control and wield this powerful tool in future gene editing. The ethical and moral questions are very difficult, and Doudna/Sternberg don't pretend to have soli...

Adeyemi rated it ★★★★★

June 26, 2017

Last time a book gave me this feeling of awe and amazement was reading Stephen Hawkin's "Brief history of time" 20 years ago. It speaks volumes to Jennifer's ability to distilled the essential on this complex topic that I left feeling I had a good grasp on the subject (albeit with my mind racing...

Bria rated it ★★★☆☆

July 18, 2017

I won this book in a Goodreads giveaway! Definitely a subject I'd be interested in but maybe I wouldn't have pursued it otherwise, so thanks Goodreads. Me being me, I found myself turned off by the personal element of the book. It's a good writing technique - it personalizes all the scientific inf...

Tony rated it ★★★☆☆

August 18, 2017

A CRACK IN CREATION: Gene Editing and the Unthinkable Power to Control Evolution. (2017). Doudna & Sternberg. ***. This work is a short history of CRISPR, a term that refers to a region of bacterial DNA. The acronym stands for “clustered regularly interspaced short palindromic repeats.” The a...

Nikki rated it ★★★★★

October 14, 2017

If you haven’t heard of CRISPR before, chances are you’ll be hearing of it again pretty soon. It’s starting to be used in clinical trials to edit the genes of human embryos, and it’s already being used in countless research projects. It’s an amazing tool which could completely revolutionise gene...

Kerry rated it ★★★☆☆

July 11, 2017

The biology of CRISPR/CAS in book are well done, but the ethics of its use less so -both in terms of clarity and thoughtfulness (not surprising given authors' background), but also some very wishful thinking (including little consideration of the inevitability of the race to the bottom (due marke...

Amy rated it ★★★★☆

August 27, 2017

This book invokes the fear of nuclear war in its summary, "Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use." However, this book DOES NOT properly address the potential for CRISPR-enhanced bio-warfare or bio-accidents within its contents...

Will rated it ★★★★★

September 28, 2017

From studying how bacteria fight off viral infections to development of the Life (not personal but humanity) changing technologies of CRISPR/Cas9. This book a great, mostly understandable primer on the development and technologies used. Understandable even for a 61 year old who has no microbiolog...

Lauren rated it ★★★★☆

September 06, 2017

A fascinating but anxiety inducing read. The technology that allows us to edit our Human DNA easily and relatively inexpensively is now here. This technology has the potential to help cure numerous genetic diseases and disorders from cancer to HIV to Muscular Distrophy, however it also comes with...

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